It's a fascinating subject. I don't have nearly enough scientific knowledge to have a truly informed opinion, but I read about this stuff sometimes and try to understand it (along with cosmology and other topics in physics that are over my head, and will probably remain so). Until watching that video, I was firmly in the camp of: 'statistically there must be life out there.' I found this lecture interesting in that he demonstrates that, based on our current understanding of life, and in lieu of meaningful data to evaluate certain variables, this argument is fairly meaningless at present. I also found the bit on extremophiles really interesting. Of course, he doesn't say there isn't life out there, just that our reasoning for assuming there is, isn't sound. My own intuition is that there definitely could and maybe should be life out there, but, again, what do I know?
And again, if so, is there a reason?